These are amateur photographs made in a general purpose biology lab. They should not be construed as textbook examples.
Discussion: In this image, again the microscope focal plane has been adjusted. Most of the cells in the center of the slide image display bright regions of light passage, yet the two marked cells do not.
What I would like to know are answers to the following questions. (1) Is there any indications that Hereditary Spherocytic Hemolytic Anemia becomes more grave as one ages? That is, would anyone having the condition expect a fairly constant level of occurrence of spheroid red blood cells, or is there evidence that the portion of abnormally shaped cells fluctuates over time. (2) Has there been discovered any linkage between HSHA and Pernicous Anemia? It's apparent why having both conditions would present severe adverse impact on a person's blood supply, but do the two occur together frequently -- or are there situations in which one acquires Pernicious Anemia. If you happen to know a hematologist, or if you happen to be a hemotologist, I'd be grateful to have you with answers to these questions, or just to initiate discussion.